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47,382 entries indexed · updated 4 min ago

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Cardiovascular3,241

Endocrine2,187

Drug Interactions8,904

Neurological4,552

Respiratory1,893

Renal / Urology2,108

Hematology1,447

Infectious Disease3,876

metformin + renal impairment|⌘K

Metformin — Renal Dose Adjustment

CKD Stage 3b–5eGFR < 30

CRITICAL

Metformin + Contrast Media Interaction

Hold 48hLactic acidosis risk

MODERATE

Metformin Pharmacokinetics in AKI

AccumulationMonitoring required

INFO

Metformin — Renal Dose Adjustment

CRITICALUpdated Jan 2026 · NICE Guidelines

eGFR (mL/min)	Action	Severity
≥ 45	Continue at full dose	LOW
30–44	Reduce dose, monitor	MODERATE
< 30	CONTRAINDICATED	CRITICAL

Risk of lactic acidosis increases significantly when eGFR drops below 30. Discontinue before iodinated contrast procedures. Resume 48h post-procedure if renal function stable.

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3 results

Electrolyte DisordersMODERATE

Hypokalemia — Clinical Presentation

Serum K+ < 3.5 mEq/L. Muscle weakness, cramps, cardiac arrhythmias. ECG: flattened T-waves, U-waves.

ElectrolytesCardiology

2 days ago

Drug ToxicityCRITICAL

Digoxin Toxicity — Recognition & Management

Nausea, visual disturbances, bradycardia. Potentiated by hypokalemia. Digoxin-specific antibody fragments (Fab) for severe cases.

CardiologyDrug Safety

1 week ago

PharmacologyLOW RISK

Loop Diuretics — Electrolyte Monitoring

Furosemide causes K+, Mg2+, Ca2+ wasting. Monitor electrolytes every 48–72h in acute settings.

DiureticsMonitoring

3 days ago

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47,208 entries across
8 specialties

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Cardiovascular

3,241

entries

Endocrine

2,187

entries

Neurological

4,552

entries

Drug Interactions

8,904

entries

Respiratory

1,893

entries

Renal & Urology

2,108

entries

Hematology

1,447

entries

Infectious Disease

3,876

entries

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3,800+

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Metformin — Renal Dose Adjustment

Every condition. Every interaction. One search.

Feel the search speed

Hypokalemia — Clinical Presentation

Digoxin Toxicity — Recognition & Management

Loop Diuretics — Electrolyte Monitoring

47,208 entries across8 specialties

Built for the bedside,not the library

Your next shift starts in two clicks

47,208 entries across
8 specialties

Built for the bedside,
not the library